Alexander disease (MR).

PROTOCOL:

T1W – Sagittal & axial scans

T2W – Axial & coronal scans

FLAIR – Axial scans

FINDINGS:

-Evidence of bilateral symmetrical increased T2 frontal white matter signal is noted. These signals are also affecting both basal ganglia including caudate nucleus; Globus pallidus in a decreasing manner.

-Evidence of faint left peri ventricular abnormal enhancement is observed.

-Prominent ventricular system is noted.

-No focal mass lesion is seen.

-Septum is in midline.  There is no midline shift.

-Basal cisterns, cortical sulci and gyri are normal in appearance.

-Sella is normal in appearance.

-Corpus callosum thinned out with upward bowing suggestive of lateral ventricular dilatation.

-Brain stem and cerebellum show normal signal intensities. 

OPINION:

·        Picture is suggestive of Alexander disease with clinical infantile onset.

·        Mega cisterna magna.

Reported By : DR.MOHAMMED MOHYELDIN

                          Consultant-Radiologist

Report Status : Validated / Validated By :  Dr.Mohammed Mohyeldin